General Recommendations: Suggest against routine screening for 25(OH)D levels in healthy adults, adults with dark complexion, and adults with obesity. Suggest daily, lower-dose vitamin D for those aged 50 years and older who have indications for vitamin D supplementation or treatment, rather than intermittent, higher-dose vitamin D.
Thresholds for Vitamin D: The panel did not establish specific 25(OH)D thresholds for disease prevention due to the lack of supporting clinical trial evidence. Previous target levels for 25(OH)D, such as 30 ng/mL (75 nmol/L), are no longer endorsed.
Nonpregnant Adults (<50 years): Suggest against empiric vitamin D supplementation above the Dietary Reference Intakes (DRI) established by the Institute of Medicine (IOM). Suggest against routine 25(OH)D testing in this population.
Adults (50-74 years): Suggest against routine vitamin D supplementation above the DRI.Suggest against routine 25(OH)D testing in this population.